Merkel Cell Carcinoma of the Upper Eyelid: When Reconstruction Becomes a Challenge

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Merkel Cell Carcinoma of the Upper Eyelid: When Reconstruction Becomes a Challenge

Merkel cell carcinoma (MCC) is a rare and aggressive tumor arising from Merkel cells located in the basal layer of the epidermis and in the hair follicle. MCC presents primarily in Caucasians (98.3%) with a median age of 69 years. Ultraviolet radiation exposure and immunosuppression appear to play a role in the development of this cancer [1]. MCCs display an aggressive clinical course with a hi...

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[Merkel cell carcinoma of the eyelid: a case report].

PURPOSE/METHODS We report the case of a 73-year-old white female suffering from Merkel cell carcinoma (MCC) of the eyelid with an evolution of two and half months. MCC is a cutaneous neuroendocrine malignant tumor arising from Merkel cells. These cells are common along the eyelid margin in between the eyelashes. It is infrequent but highly aggressive and with potential metastases. Immunohistoch...

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Merkel Cell Carcinoma of Eyelid: A Rare Clinical Presentation and Diagnostic Challenge

The purpose of this paper is to report a case of rare localised (limited to eyelid) malignant eyelid tumor in a 70 year old Indian male. Histopathology confirmed it to be a Merkel cell carcinoma. Surgical excision and eyelid reconstruction was done successfully. No local or systemic recurrence has been noted at a follow up of 2 years. The well defined nature of a highly malignant tumor, its loc...

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Merkel Cell Carcinoma of the Eyelid and Periocular Region

Merkel cell carcinoma (MCC) in the eyelid and periocular region can be treated surgically, in most cases, with preservation of the eye and reasonable visual function. Adjuvant radiation therapy, sentinel lymph node biopsy, and chemotherapy should be considered for MCC of the eyelid and periocular region, especially for larger tumors that are T2b or more advanced and lesions that present with re...

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Merkel cell carcinoma of the eyelid: management and prognosis.

IMPORTANCE The literature on Merkel cell carcinoma (MCC) of the eyelid remains scarce, and there has yet to be a study using the most up-to-date TNM staging system for this rare but aggressive tumor. OBJECTIVE To analyze the TNM stage, management, and outcomes of patients with MCC of the eyelid. DESIGN, SETTING, AND PARTICIPANTS Retrospective case series of 21 patients from 5 tertiary refer...

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ژورنال

عنوان ژورنال: Archives of Plastic Surgery

سال: 2015

ISSN: 2234-6163,2234-6171

DOI: 10.5999/aps.2015.42.2.257